Simparica can be offered by hand, in the food, or administered like other tablet medications. It is also used off-label to control sarcoptic mange and demodectic mange. Buy Simparica Chewable Tablet for Dogs, 44. Fortunately for conscientious dog moms and dads, Simparica offers a once-a-month chewable treatment that is FDA-approved and safe for Fido, taking the guesswork out of fighting fleas and ticks. PARSIPPANY, N. Simparica dog chewables are now available in beef, pork, lamb,veal, goat, chicken, turkey, chicken meal, fish, venison, bison, and sardines. Product Description. . 6 and 11 pounds 1. Which means you can be confident knowing between each. Simparica prevents and treats infestations with fleas and ticks. 78. 79 Autoship Price. Save £21. Write a Review. 27 mg/lb (5 mg/kg) pyrantel (as. 6-5 kg. 9 percent in preventing brown dog ticks, deer ticks, Gulf Coast ticks, Lone star ticks, and American dog ticks. Quick View. Dogs weighing 2. Had to take him to the vet over the weekend for intractable diarrhea when progressed to vomiting, anorexia and understandably lethargy after simparica trio. Available As Chewables For use with Canine Strengths 5 mg 10 mg 20 mg 40 mg 80 mg 120 mg Pack sizes 1 tablets 3 tablets 6 tablets To order Overview Ticks Fleas Overview Simparica Acts Fast See full list on 1800petmeds. Each tablet is formulated to provide minimum dosages of 1. Simparica (sarolaner) Chewables are a well-tolerated, flea, tick and mite protection for dogs that start working. Simparica Flea and Tick Chews for Small Dogs. Simparica has not been evaluated in dogs that are pregnant, breeding or lactating. Simparica is the only monthly tick and flea chewable for dogs approved to kill 5 types of ticks: Gulf Coast tick, Brown dog tick, Deer tick/black-legged tick, American dog tick, Lone Star tick. You save 59%. Both Bravecto and Simparica offer effective and fast-acting prevention against fleas and ticks. Simparica Trio is a monthly chewable tablet for dogs that provides comprehensive protection against fleas, ticks, heartworms, and intestinal worms. Simparica is a chewable flea and tick medication for dogs that is more recommended for full spectrum tick protection for dogs because it kills five types of ticks. £29. 1 Unlike others on the market,. Buy Simparica Chewable Tablet for Dogs, 22. More Choices Available. This once-a-month tablet gives you an easy, reliable way to protect your dog from fleas and ticks. Nexgard does not last as long or provide the same powerful performance. Simparica Trio contains three active ingredients. Simparica provides immediate and persistent flea killing activity up to and beyond the monthly treatment interval, minimising the risk of protection gaps. With the ingredient. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. Simparica Trio is formulated using Sarolaner, Moxidectin, and Pyrantel, while NexGard Spectra contains Afoxolaner and Milbemycin Oxime. Some limitations and restrictions may apply. The most common adverse reactions in clinical trials were vomiting and diarrhea. 0 lbs should be given one 10 mg Simparica chewable tablet monthly. Simparica è un farmaco veterinario antiparassitario, specifico per il cane, indicato per il trattamento di infestazioni da: zecche. This medication contains a powerful Sarolaner, a powerful isoxasoline drug, which the FDA warns can produce serious. In one study, nine of the tenDe ação rápida, Simparic faz efeito em 3 horas e se mantém por até 35 dias. 15% discount available for new customers only. Simparica Trio treats and protects against harmful parasites. com. 5 lbs 5. 00 – $ 302. Simparica is a tasty, chewable tablet that should be given by a dog's weight to those older than 6 months. Simparica (sarolaner) Chewables are safe, monthly flea and tick protection for dogs that start working fast and remain effective all month long. Most dogs readily take this chewable tablet. Pas d'effets secondaires, cela fait maintenant plusieurs années que mon chien est traité avec ces cachetsSimparica Trio is an advanced liver-flavored chewable treatment designed specifically for dogs and young puppies. The active ingredients in Simparica Trio are sarolaner, moxidectin, and pyrantel. SIMPARICA ® (sarolaner) is a flavoured chewable tablet containing 5, 10, 20, 40, 80, or 120 mg of sarolaner, an ectoparasiticide intended for administration to dogs according to their weight. It’s a monthly oral flea and tick treatment which comes in form of a tasty Liver- flavored chewable tablet. 1 x 40mg tablet for 22. 99, which is -12% off the average retail price of $161. Fleas and ticks, intestinal worms and deadly heartworm. 4. By clicking 'Accept' you confirm that this describes you. Simparica for dogs is a medication designed to prevent this. 8 to 5. S. 048 mg/kg of moxidectin and 5–10 mg/kg of pyrantel in accordance with the following table: Bodyweight (kg) Tablet strength 3 mg/0. Simparica is for use only in dogs 6 months of age and older. It is notably a medication for protection from Gulf coast. Como tratar intoxicação de ivermectina em gatos? O tratamento das intoxicações causadas pela ivermectina requer suporte e fluidoterapia intensa com cristalóides. The regular use of these products is thought to give nearly 100% protection against ticks, although checking is still recommended. Medicare. The safe use of Simparica TRIO has not been evaluated in breeding, pregnant, or lactating dogs. It can treat 5 parasites at a time and can protect well against heartworm disease, ticks & fleas, roundworms even hookworms. Based on official information, simparica is for treatment related to the flea and tick. The palatable liver-flavored chewable. Simparica is the only monthly tick and flea chewable for dogs approved to kill 5 types of ticks: Gulf Coast tick, Brown dog tick, Deer tick/black-legged tick, American dog tick, Lone Star tick. 6-11 lbs 11. Free shipping and price match available. 011 mg/lb (24 μg/kg) moxidectin, and 2. 99. simparica chewables is a fast acting oral flea and tick preventative tabs that begins killing fleas and ticks within hours of administration and remains effective for one month to prevent re-infestations. Save 15% On Your Purchase with Simparica Flea And Tick Medication Coupon Code. 1-132 lbs is $99. Sarolaner, sold under the brand name Simparica, is an ectoparasiticide veterinary medication for the treatment of flea and tick infestations in dogs. 12 mg/25 mg. Starting 12/31/2023, WalmartPetRx. 5 pounds. Simparica Chewable Tablet for Dogs, 88. Keep SIMPARICA in a secure location out of reach of dogs, cats and other animals to prevent accidental ingestion or overdose. Simparica Trio is a widely used flea and tick preventative medication for dogs. It’s the newer tablet-based Isoxazoline products that are the real game changers. Simparica chewable tablets for dogs. 8 pounds or greater. 1 Simparica is FDA-approved to block infections that may cause Lyme disease by killing deer ticks. Administrar doses seriadas de carvão ativado na dose de 1 a 5 g/kg VO, TID, catárticos salinos aumentam a eliminação da ivermectina, excretada principalmente pela via fecal. Simparica has been safely used in dogs treated with commonly prescribed vaccines, parasiticides and other medications. Simparica Trio Results Value: Simparica Trio Both preventatives are have six weight brackets to choose from: 2. Some mild simparica side-effects usually disappear within 48 hours without veterinary intervention, while severe ones may take days to weeks. Contents hide. The most frequently reported adverse. 1-132 lbs, (Brown Box), 3 Chewable Tablets (3-mos. 011 mg/lb (24 µg/kg) moxidectin, and 2. It contains sarolaner, which kills fleas and ticks, moxidectin, which helps prevent heartworm disease and pyrantel, which treats and controls roundworm and hookworm. Nexgard is given every four weeks. Simparica brings a new innovative way to keep on top of fl eas and ticks by providing immediate and persistent killing activity for at least 35 days , acting beyond the monthly treatment period. diseases caused because of them. Starting 12/31/2023, WalmartPetRx. 8 pounds. Simparica TRIO with a detailed product breakdown. It can also prevent new infestations of. 27 or 16. Simparica Trio is a once-monthly chewable tablet that can treat existing flea and tick infestations and help prevent fleas, ticks, heartworm, roundworm and hookworm. I give this product an overall rating of a 4. These ingredients also prevent heartworm disease, and treat and control intestinal worms. Currently, these are Nexgard®, Bravecto® and Simparica®, and Credelio®. Drug Info. 8 pounds and greater. Coupon Codes 5. If a dose is missed, administer SIMPARICA and resume a monthly dosing. Simparica has not been evaluated in dogs that are pregnant, breeding or lactating. 15% discount available for new customers only. 40/Gram) $17. QUALITATIVE AND QUANTITATIVE COMPOSITION Each tablet contains: Active substances: Simparica Trio chewable. This ingredient stops the neurotransmitter gamma aminobutyric acid (GABA) receptor from functioning, along with the glutamate receptor, and affects the neuromuscular junction in fleas, which. View as Grid List. A 6-month supply of chewable Simparica tablets ranges in price from $80 to $100 on average. The chews also help in eliminating fleas and ticks including five tick types: Black-legged ‘deer’ ticks, American dog ticks, Gulf Coast ticks,. Twintanica. 91 mg/lb (2 mg/kg). Each tablet is formulated to provide a minimum sarolaner dosage of 2 mg/kg (0. Each tablet is formulated to provide minimum dosages of 1. The main goal. Sarolaner is an acaricide and insecticide belonging to the isoxazoline group. Simparica Trio Chewable Tablets for Dogs 44. Simparica TRIO (sarolaner/moxidectin/pyrantel) is a flavored chewable tablet for administration to dogs 8 weeks of age and older. See full Prescribing Information. There are also “store brand” versions of these that you. FREE shipping and the BEST customer service! Simparica Trio Chewable Tablets for Dogs works to prevent heartworms as well as treat lone star ticks, black-legged ticks, Gulf Coast ticks, American dog ticks, brown dog ticks, fleas, roundworms, and adult hookworms. Need flea medicine for extra large dogs or small dogs? There are 6 different dosage options depending on your dog’s weight, ranging from 2. 0 lbs should be. $51. Simparica Chewable Tablet for Dogs 44. SIMPARICA TRIO (sarolaner, moxidectin, and pyrantel chewable tablets) is a flavored, chewable tablet for administration to dogs 8 weeks of age and older. Simparica is a fast-acting oral flea and tick preventative that begins killing fleas and ticks within hours of administration and remains effective for one month to prevent re-infestations. I give this product an overall rating of a 4. Given a chewable texture and a palatable flavour for ease of administration, Simparica works by acting on the parasites nervous system, inducing paralysis and. Simparica Trio is a once-a-month, easy-to-give chewable that helps simplify protecting your pet every month. You can use Simparica Flea and Tick Medication monthly to keep your dogs safe from these pesky parasites. Environments with warm climates, wooded areas, or those in proximity to wildlife can heighten a dog’s exposure to these parasites. Have a look at this table of comparison between Simparica. A product from the house of Zoetis, Simparica Chewables has turned out to be an avant-garde in the domain of flea and tick treatments. Simparica Trio is an advanced liver-flavored chewable treatment designed specifically for dogs. Neoterica Protecto 4 Flea and Tick Prevention for Dogs & Puppies - Flea Medicine & Home Pest Control - Topical Treatment & Mosquito Repellent for Dogs - Small, Medium and Extra Large Drops in Pack. 8 pounds or more. It helps to prevent home infestations and tick-borne illnesses. Simparica has been safely used in dogs treated with commonly prescribed vaccines, parasiticides and other medications. When comparing the prices of Nexgard and Simparica, they are close. It is exclusively indicated when use against ticks or fleas, and gastrointestinal nematodes are indicated at the same time. 00. Simparica Trio is approved for dogs eight weeks of age and older weighing 2. Since coming to the attention of Zoetis, the company is. It is exclusively indicated when use against ticks or fleas, and gastrointestinal nematodes are indicated at the same time. Side Effects: Short-term illness. It contains three active ingredients: sarolaner, moxidectin, and pyrantel, which work together to provide comprehensive protection against multiple parasites. 99 Chewy Price. When comparing NexGard to Simparica Gulf Coast ticks could be a deciding factor. Simparica kills adult fleas, and is indicated for the treatment and prevention of flea infestations, and the treatment and control of tick infestations from lonenstar ticks, Gulf Coast ticks, American dog tick, black-legged ticks and brown dog ticks for one month in dogs 6 months of age or older and weighing at least 2. acari dell'orecchio. Simparica contains sarolaner, which enters your dog’s bloodstream after being absorbed through the stomach. 6 and 11 pounds 1. 2% effectiveness, proving its worth as a reliable preventive medication. 1 Simparica Trio is an FDA-approved prescription medication that can help to prevent a number of infections caused by parasites, including those of which can lead to Lyme disease, caused by deer ticks. No adverse effects were observed at the maximum dose of 4 mg/kg. Simparica TRIO (sarolaner/moxidectin/pyrantel) is a flavored chewable tablet for administration to dogs 8 weeks of age and older. Simparica is given orally once a month at the recommended minimum dosage of 0. Simparica Ingredients. It's a tasty tablet. Off-label, it is used to manage ear mite infestations, sarcoptic and demodectic mange. Say goodbye to pesky, persistent pests and hello to Simparica. By clicking 'Continue' you confirm that this describes youSimparica has 1. From the moment your dog ingests Simparica Trio, any fleas they may unknowingly be harboring will be killed in four hours. Simparica 88. The tablet contains three active ingredients - sarolaner, moxidectin, and pyrantel - that work together to kill and repel parasites. O ideal é repetir a dosagem após este período para ter um efeito contínuo no animal. Heartgard, on the other hand, is a veteran in the field, predominantly known for its effectiveness against. 4 mg/kg of sarolaner, 0. 6 to 11. Simparica Trio chewable tablets for dogs >5–10 kg Simparica Trio chewable tablets for dogs >10–20 kg Simparica Trio chewable tablets for dogs >20–40 kg Simparica Trio chewable tablets for dogs >40–60 kg 2. . If a monthly dose is missed, give SIMPARICA TRIO immediately and resume monthly dosing. 1. Simparica works faster on ticks, killing them within 12 hours of jumping on and feeding. In isolated cases, however, dogs displayed. Simparica Trio has the potency to kill five types of ticks including: Gulf coast tick, American dog ticks, Lone star ticks, Deer ticks and Brown dog ticks. Simparica has been safely used in dogs treated with commonly prescribed vaccines, parasiticides and other medications. This monthly chewable Simparica Trio is 100% protection and the advanced product among all. Simparica Trio is a potent and reliable medication that safeguards your furry friends against some of the most common parasites. Keep SIMPARICA in a secure location out of reach of dogs, cats and other animals to prevent accidental ingestion or overdose. SIMPARICA from ZOETIS is another once-a-month chewable tablet for flea + tick + mange mite control in dogs. Flea and tick worm infestation can be irritating for your dog and you as a dog owner. Monthly Simparica Trio prevents heartworm disease, kills adult fleas and is indicated for the treatment and prevention of flea infestations, the treatment and control of tick infestations, and the treatment and control of roundworm and hookworm infections in dogs and puppies 8 weeks of age and older, and weighing 2. 2 mg/kg)Simparica Trio is a once-a-month, easy-to-give chewable that helps simplify protecting your pet every month. Heartgard uses Ivermectin to prevent heartworm disease, while Nexgard uses Afoxolaner to tackle fleas and ticks. Each tablet is formulated to provide minimum dosages of 0. Let’s analyze the product little profoundly. Simparica Trio for Dogs. QUALITATIVE AND QUANTITATIVE COMPOSITION. Simparica TRIO contains three active pharmaceutical ingredients, sarolaner, moxidectin, and pyrantel pamoate. . S. 2. 4. Simparica Trio protects dogs from heartworms and other worms, plus fleas and ticks, all in one chewable pill. Understand your pet’s specific needs, consult with your veterinarian, and make an informed choice. 68. 2, respectively, and for the Simparica Trio™ groups were 0 and 0. 1 to 11 pounds, 11. Many traditional (and even some holistic) veterinarians are strongly recommending the use of the isoxazoline class of pSimparica Trio is a powerful, chewable medication designed to protect your four-legged friends from heartworm disease, ticks, fleas, and several internal parasites. Simparica Trio is FDA. Your credit card statement will reflect a charge by Vetsource for your purchase. If you’re someone who doesn’t want to have to treat their dog every month, then Bravecto is the product for you. Dogs get all this protection with just one dose of Simparica Trio. In laboratory safety studies, no interactions were observed when sarolaner was co-administered with milbemycin oxime, moxidectin and pyrantel pamoate. Simparica Trio is the first and only product that combines sarolaner, moxidectin and pyrantel in each treatment to help prevent heartworm disease, kill fleas before they can lay eggs, kill 5 types of ticks, treat and prevent flea infestations and treat and control roundworms and hookworms. Simparica is indicated for the prevention of Borrelia burgdorferi infections as a direct result of killing lxodes scapularis vector ticks. 91 mg/lb (2 mg/kg) sarolaner. This product is sourced in the United Kingdom and is intended for use in the United Kindgom only. If this occurs, notify your veterinarian. Buy Simparica Trio Chewable Tablets for Dogs recommended for use in dogs and puppies 8 weeks of age and. 1-88 lbs is $98. Simparica TRIO® was also 90 to 100% effective at preventing B. If your dog doesn't have those issues, you should be fine. 8-5. Para fazer efeito, a dose deve ser dada de acordo com o peso do animal. See full Prescribing Information. Simparica. SIMPARICA ® (sarolaner) is a flavoured chewable tablet containing 5, 10, 20, 40, 80, or 120 mg of sarolaner, an ectoparasiticide intended for administration to dogs according to their weight. 54 milligrams of sarolaner, 0. The most recommended flea treatment will depend on your dog and your specific preferences as a pet parent. 1-132 lbs is $99. 4 mg/kg of sarolaner, 0. To make dosing easy, it's available for dogs in six sizes based on body weight range: Gold: 2. $63. Sarolaner is a class of neurotoxin. 61 per dose. 27 per dose. 9%) voluntarily consumed by free choice without, or when offered in food. Simparica 20mg Chewable Tablets are tasty chewable tablets used to treat tick, flea and sarcoptic mange infestations in dogs weighing >5kg - 10kg for up to 5 weeks. Simparica chewable tablets for dogs. 1 to 44 pounds. 8. 5. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that. 48 or $15. supply) at Chewy. 1 to 44 pounds, 44. $52. I can feel her body trembling, and it. By Company. Simparica does cost more per box, but the weekly price differences are between $. Simparica has not been evaluated in dogs that are pregnant, breeding or lactating. 1-88 lbs is $98. Simparica Trio starts killing fleas within 4 hours and has a 100% effectiveness rate within 8 hours for the entire month. Simparica is a monthly flea and ticks tablet for dogs that provides broad-spectrum protection for 35 days. Side Effects. Reviews 360 reviews. Simparica prevents and treats infestations with fleas and ticks. Compare Simparica vs. Simparica Trio is a once-monthly chewable tablet that can treat existing flea and tick infestations and help prevent fleas, ticks, heartworm, roundworm and hookworm. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. It starts working fast* and goes strong for 35 days. However, as with any medication, it's important to understand the potential side effects and how long they might last. Simparica is the only oral treatment that provides comprehensive protection against five types of ticks such as American dog ticks, Lone star ticks, Gulf Coast ticks, Brown dog ticks, Black-legged ticks in 6 months, and old dogs that weigh 2. SIMPARICA 120 mg (chewable tablets for dogs). Simparica è vendibile esclusivamente previa ricetta medica, dunque NON è un farmaco di libera vendita. 99. Sarolaner is also a component of the combination drug Simparica Trio, which contains sarolaner, moxidectin, and pyrantel. It can also prevent new infestations of these pests. Get 20% off your first Chewy Pharmacy order with code GOODRX20. When used on adult dogs weighing 2. : G4321 (Act 36/1947). It kills ticks as well as fleas. The treatment lasts for 35 days so monthly use is sufficient to keep your dog. 1x 10mg tablet for 5. Consult your veterinarian. Currently, for Simparica, less than 0. However, on average, a 6-month supply of Simparica Trio will cost around $180. Get Simparica Discount Code and find Black Friday Coupons & Deals. 5 out 5 in ratings from a vet’s viewpoint. It’s also important to keep in mind that a single Bravecto dose can offer 12 weeks of parasite protection. Simparica is a safe, monthly chewable tick and flea preventative for dogs. After Simparica is given its activity against ticks and fleas lasts for at least 5 weeks. Simparica has not been evaluated in pregnant, breeding or lactating dogs. When fleas or ticks bite, they are exposed to. Trifexis. No worms were recovered from any of the Simparica Trio™-treated dogs in Study 1, and only 2 worms were recovered from a single Simparica Trio™-treated dog in Study 2. This monthly oral treatment helps in. 50 and $1. It is given once a month via a chewable tablet and starts killing fleas and ticks within hours. It is indicated for the effective control of fleas and ticks. Simparica may cause abnormal neurologic signs such as tremors, unsteadiness, and/or seizures. Dogs get all this protection with just one dose of Simparica Trio. For 1 tab, effects lasts for 1 whole month. Isoxazoline based products used for prevention and treatment of fleas, ticks, and mites (Bravecto, Bravecto Plus, Nexgard, Simparica, Simparica Trio, Credelio, Revolution Plus) are gaining popularity. 1 Simparica is FDA-approved to block infections that may cause Lyme. 5. Rating DistributionSIMPARICA ® (sarolaner) is a flavoured chewable tablet containing 5, 10, 20, 40, 80, or 120 mg of sarolaner, an ectoparasiticide intended for administration to dogs according to their weight. Simparica Trio can be described as a broad-spectrum parasite preventative that offers protection and treatment to dogs. Heartworm Prevention SIMPARICA TRIO should be administered at. With its rapid action and 35-day duration of protection, Simparica ensures. 3–2. Simparica:. Original review Jun 21, 2022. 3. Simparica Trio contains Moxidectin, Sarolaner, and Pyrantel, addressing a wide range of parasites. Dogs get all this protection with just one dose of Simparica Trio. 1 to 88 pounds, or 88. 8 lbs / 1. Zoetis UK Limited. The most frequently reported adverse reactions were vomiting and diarrhea. Description. It contains the active ingredient sarolaner, which is a potent insecticide that works by targeting the nervous system of fleas and ticks, killing them quickly. Active Ingredient. Product Deals 0. 25 kg. Simparica Trio starts killing fleas within 4 hours of administration, whereas, NexGard Spectra begins killing fleas within 6-8 hours of administration. 0%. Simparica Trio is an all-in-one parasitic preventative. Sort by. It's a tasty tablet that works to shield your pet for a full 35 days, killing fleas before they can lay eggs. Simparica kills newly emerged fleas on the dog before they can lay eggs therefore preventing environmental flea contamination 1. This product offers added protection against whipworms, and the rapidly-acting formula kills 100% of biting. 5 pounds. Overall, Simparica scores 4. 9 and 29. Simparica Cost. Simparica works by entering your dog’s bloodstream and due to the nature of its active ingredient ‘Sarolaner’, it becomes an ectoparasiticide to effectively kill any parasite. Sarolaner is extremely effective against invertebrates like fleas and. Sarolaner is an acaricide and insecticide belonging to the isoxazoline group. Simparica contains Sarolaner as its active ingredient, which is a member of the isoxazoline family. Simparica tablets take about 3 hours to eliminate fleas and about 8 hours to eliminate ticks. After 1 emergency vet visit and a number of consultations with our primary care vet, we took him off simparica. There are some differences between these two options that should be considered before you make your decision. The material contained within this website is intended to be viewed by UK practising veterinary surgeons only. Both Capstar and Simparica have their unique strengths and serve different purposes. 1 to 132 pounds, along with three options for the number of chewables to purchase at one time: three, six, or twelve. Simparica contiene il principio attivo sarolaner. March 2016 saw the addition of Simparica, yet another so-called Isoxazoline flea and tick “remedy”… and already several dogs have been adversely affected by this new drug. 1-88 lbs, (Green Box), 3 Chewable Tablets (3-mos. How to say Simparica in English? Pronunciation of Simparica with 4 audio pronunciations and more for Simparica. Qual a dosagem de. 8 to 5. Simparica is a trusted oral medication for dogs that provides adequate monthly protection against fleas and ticks. 8 to 5. Both are effective flea treatments. It's a flavored, chewable tablet used by or on the order of a licensed veterinarian to: Prevent Borrelia burgdorferi infections caused by the killing of Ixodes scapularis vector ticks. Simparica offers a hamburger-size portion as well as parts of chicken. Simparica's active ingredient, Sarolaner, begins to kill fleas within 3 hours and ticks within 8 hours. Type: Over-the-counter, topical | Active ingredients: Imidacloprid, permethrin, and pyriproxyfen. Proven persistent protection against. . With three active ingredients designed for defense, Simparica Trio keeps dogs protected from heartworm disease,. 8. Simparica TRIO contains three active pharmaceutical ingredients, sarolaner, moxidectin, and pyrantel pamoate. Simparica Trio can be described as a broad-spectrum parasite preventative that offers protection and treatment to dogs. 1-10 kg. FREE delivery Fri, Nov 10 on $35 of items shipped by Amazon. With three active ingredients designed for defense, Simparica Trio keeps dogs protected from heartworm disease, fleas & ticks, and roundworms & hookworms. 8 to 5. Simparica may cause abnormal neurologic signs such as tremors, unsteadiness, and/or seizures. Très bon produit pour les chiens allergiques aux tiques. With three active ingredients designed for defense, Simparica Trio keeps dogs protected from heartworm disease, fleas & ticks, and roundworms & hookworms.